In this Medicinal Chemistry story, I describe the discovery of ibuprofen, one of the world's most successful anti-inflammatory drugs. What began as a search...
🌿 Birch Reduction – Overview
The Birch reduction is a partial reduction of aromatic rings using:
Sodium (Na) or lithium (Li) metal
In liquid ammonia (NH₃)
With an...
SN1 reactions are substitution reactions where the rate-determining step involves only one molecular entity, making the reaction unimolecular.
Mechanism:
Formation of Carbocation (Rate-Determining Step):
The leaving group...
In this Medicinal Chemistry story, I describe the discovery of ibuprofen, one of the world's most successful anti-inflammatory drugs. What began as a search...
